The emerging role of extracellular vesicles in bronchopulmonary dysplasia

Extracellular vesicle (EV) biology in neonatal lung development and disease is a rapidly growing area of investigation. Although EV research in the neonatal population lags behind EV research in adult lung diseases, recent discoveries demonstrate promise in furthering our understanding of the pathop...

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Bibliographic Details
Published in:	American journal of physiology. Lung cellular and molecular physiology Vol. 326; no. 5; p. L517
Main Authors:	Ransom, Meaghan A, Blatt, Alexander M, Pua, Heather H, Sucre, Jennifer M S
Format:	Journal Article
Language:	English
Published:	United States 01-05-2024
Subjects:	Animals Biomarkers - metabolism Bronchopulmonary Dysplasia - metabolism Bronchopulmonary Dysplasia - pathology Bronchopulmonary Dysplasia - physiopathology Extracellular Vesicles - metabolism Extracellular Vesicles - pathology Humans Infant, Newborn Lung - metabolism Lung - pathology bronchopulmonary dysplasia extracellular vesicles
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Summary:	Extracellular vesicle (EV) biology in neonatal lung development and disease is a rapidly growing area of investigation. Although EV research in the neonatal population lags behind EV research in adult lung diseases, recent discoveries demonstrate promise in furthering our understanding of the pathophysiology of bronchopulmonary dysplasia and the potential use of EVs in the clinical setting, as both biomarkers and therapeutic agents. This review article explores some of the recent advances in this field and our evolving knowledge of the role of EVs in bronchopulmonary dysplasia.
ISSN:	1522-1504
DOI:	10.1152/ajplung.00244.2023