Cytogenetic findings in T-zone lymphoma

Five cases of T-zone lymphoma were investigated with histologic, immunologic, and cytogenetic methods. The chromosome analyses were performed on lymphoma cells prepared immediately after removal of the lymph nodes. The chromosomes involved in structural rearrangements were nos. 1, 2, 3, 4, 14, and Y...

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Bibliographic Details
Published in:	Journal of cancer research and clinical oncology Vol. 101; no. 1; pp. 81 - 89
Main Authors:	Gödde-Salz, E, Schwarze, E W, Stein, H, Lennert, K, Grote, W
Format:	Journal Article
Language:	English
Published:	Germany 01-01-1981
Subjects:	Aged Chromosome Aberrations Humans Karyotyping Lymphocytes - immunology Lymphocytes - ultrastructure Lymphoma - immunology Lymphoma - pathology Male Middle Aged T-Lymphocytes - pathology
Online Access:	Get full text
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Summary:	Five cases of T-zone lymphoma were investigated with histologic, immunologic, and cytogenetic methods. The chromosome analyses were performed on lymphoma cells prepared immediately after removal of the lymph nodes. The chromosomes involved in structural rearrangements were nos. 1, 2, 3, 4, 14, and Y. Numbers 3, 5, 6, and 13 were lost by some tumors, and nos. 3 and 9 were gained. Chromosome 3 was involved most often in structural and numerical aberrations, whereas 14q + markers occurred in only one case. The importance of multidisciplinary studies is pointed out.
Bibliography:	ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3
ISSN:	0171-5216 1432-1335
DOI:	10.1007/BF00405068