Salmonella Urinary Tract Infection and Bacteremia Following Non-Typhoidal Salmonella Gastroenteritis: An Unusual Presentation

• Published in: Curēus (Palo Alto, CA) Vol. 12; no. 12; p. e12194
• Main Authors: Altaf, Areeba, Tunio, Numra, Tunio, Sameer, Zafar, Meer R, Bajwa, Numra
• Format: Journal Article
• Language: English
• Published: United States Cureus 20-12-2020
• Subjects: Infectious Disease; Internal Medicine; Urology; non-typhoidal salmonella (nts); gastroenteritis; salmonella infection; urinary tract infection; bacteremia
• ISSN: 2168-8184; 2168-8184
• DOI: 10.7759/cureus.12194

is primarily known to affect the gastrointestinal tract but can rarely cause infections at uncommon sites, such as the urinary tract. It is known that
can infect the urinary tract directly by blood, fecal contamination of urethra, urolithiasis, or secondary intraluminal ascending infection. Our patient is a 59-year-old female with a past medical history of nephrolithiasis and multiple urinary tract infections (UTI) who presented with altered mental status and sepsis complicated by
bacteremia and UTI. Urine and blood cultures revealed
species > 100,000 colony-forming units per milliliter (CFU/mL) and non-typhoidal 
, respectively. During the course of her hospital admission, the patient was treated with multiple antibiotics. On further review, it was noted that the patient had presented to the emergency room (ER) about four months earlier with abdominal pain and watery diarrhea with a stool culture being positive for non-typhoidal 
. Gastroenteritis, sepsis, and enteric fever are normally known with
(
). Less common extraintestinal diseases like UTI are due to non-typhoidal
. The most frequent pathogenesis of
UTI is probably hematogenous. UTI caused by non-typhoidal
is usually associated with structural abnormalities of the urinary tract. In our case, the patient had non-typhoidal 
gastroenteritis followed by non-typhoidal 
bacteremia and UTI.