The role of optic nerve blood flow in the pathogenesis of glaucoma

Many theories have surfaced regarding the exact mechanisms behind glaucomatous damage, but the complex nature of the disease and the inaccessibility of the internal structures of the human eye have limited current knowledge. Increased intraocular pressure is the risk factor most often associated wit...

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Bibliographic Details
Published in:	Ophthalmology clinics of North America Vol. 18; no. 3; p. 345
Main Authors:	Harris, Alon, Rechtman, Ehud, Siesky, Brent, Jonescu-Cuypers, Christian, McCranor, Lynne, Garzozi, Hana J
Format:	Journal Article
Language:	English
Published:	United States 01-09-2005
Subjects:	Aging - physiology Blood Flow Velocity Blood Pressure Glaucoma, Open-Angle - etiology Glaucoma, Open-Angle - physiopathology Humans Optic Disk - blood supply Regional Blood Flow
Online Access:	Get more information
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Summary:	Many theories have surfaced regarding the exact mechanisms behind glaucomatous damage, but the complex nature of the disease and the inaccessibility of the internal structures of the human eye have limited current knowledge. Increased intraocular pressure is the risk factor most often associated with glaucomatous optic neuropathy; ischemic insult to the optic nerve has also been suggested as a possible cause of cellular damage. The aim of this review is to cover the possible role of optic nerve head hemodynamics in the pathogenesis of glaucoma.
ISSN:	0896-1549
DOI:	10.1016/j.ohc.2005.04.001