Irritable Bowel Syndrome: Treating the Gut and Brain/Mind at the Same Time

• Published in: Curēus (Palo Alto, CA) Vol. 15; no. 8; p. e43404
• Main Authors: Jayasinghe, Maleesha, Damianos, John A, Prathiraja, Omesh, Oorloff, Melysze D, Nagalmulla K, Gairu M, Nadella, Adithya, Caldera, Dilushini, Mohtashim, Ali
• Format: Journal Article
• Language: English
• Published: Palo Alto Cureus Inc 13-08-2023; Cureus
• Subjects: Abdomen; Bacteria; Breath tests; By products; Carbohydrates; Constipation; Diarrhea; Diet; Gastroenteritis; Gastroenterology; Histamine; Inflammation; Internal Medicine; Irritable bowel syndrome; Medical diagnosis; Microbiota; Nutrition; Pain; Pathogenesis; Pathophysiology; Permeability; Psychological aspects; Small intestine; Stem cells
• ISSN: 2168-8184; 2168-8184
• DOI: 10.7759/cureus.43404

Irritable bowel syndrome (IBS) is one of the most common functional gastrointestinal (GI) disorders in the world. Although IBS does not affect a person's life span, it can significantly influence their quality of life. The treatment of IBS should be tailored to each patient's specific symptomatology because it can often be difficult to manage. Given that the pathogenesis of IBS is not well understood, it places a tremendous load on healthcare resources. Over the years, IBS has been described as either a simple GI disorder or a more complex multi-symptomatic gut-brain axis disorder. Many persons with IBS have psychological issues in addition to gastrointestinal symptoms, offering the door to non-pharmacological therapies such as cognitive behavioral therapy, gut-directed hypnosis, or psychodynamic interpersonal therapy. Non-pharmacological therapies with no side effects should be used as first-line therapy. Diet, exercise, microbiota-targeted therapies, and psychological treatments are among the most significant interventions. This review goes into the details of all the non-pharmacological interventions that can be used to treat IBS.