IgG4 Drives M2 Macrophages to Cortisol, Lcn-2 and IL-10 Release: Implications in Maintenance of Tolerance and Allergen Immunotherapy

IgG4 Drives M2 Macrophages to Cortisol, Lcn-2 and IL-10 Release: Implications in Maintenance of Tolerance and Allergen Immunotherapy

Only IgG4 is leading to cortisol, LCN-2 and IL-10 secretion. [...]exogenous unloaded lipocalin allergens may lower the levels of bioavailable cortisol, and LCN-2 and IL-10 release.

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Bibliographic Details
Published in:Journal of allergy and clinical immunology Vol. 137; no. 2; p. AB403
Main Authors: Jensen-Jarolim, Erika, Prof, Roth-Walter, Franziska, PhD, Ass.Prof, Pacios, Luis F., Prof, Wagner, Stefanie, MSc, BSc, Glenk, Lisa-Maria, Dr, Hofstetter, Gerlinde, MSc, BSc, Palme, Rupert, Prof, Roth, Georg A., Prof, Hufnagl, Karin, PhD, Bianchini, Rodolfo, PhD
Format: Journal Article
Language:English
Published: St. Louis Elsevier Inc 01-02-2016
Elsevier Limited
Subjects:
Allergy and Immunology
Immunotherapy
Ligands
Online Access:Get full text
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Description
Summary:Only IgG4 is leading to cortisol, LCN-2 and IL-10 secretion. [...]exogenous unloaded lipocalin allergens may lower the levels of bioavailable cortisol, and LCN-2 and IL-10 release.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2015.12.1248