Residual urinary output in high body mass index individuals on chronic hemodialysis:A disregarded life vest?

• Published in: World journal of nephrology Vol. 3; no. 4; pp. 317 - 323
• Main Author: Trimarchi, Hernán
• Format: Journal Article
• Language: English
• Published: United States Baishideng Publishing Group Inc 06-11-2014
• Subjects: Observational Study; Pro-BNP; Body mass index; Residual diuresis; Hemodialysis; Insulin; Troponin T
• ISSN: 2220-6124; 2220-6124
• DOI: 10.5527/wjn.v3.i4.317

AIM:To assess residual diuresis and diverse variables according to body mass index(BMI).METHODS:Cross-sectional study(n = 57),with 3groups.Group A:BMI < 25,n = 22; Group B:BMI25-30,n = 15; Group C:BMI > 30,n = 20.Diuresis,hematocrit,albumin,C-reactive protein,Malnutrition inflammatory score,Pro-BNP,Troponin T,leptin and insulin levels are expressed as median and ranges(r).RESULTS:Albumin(g/dL):GA vs GC,3.70(r2.20-4.90)vs 3.85(r3.40-4.90),P = 0.02.Diuresis(m L/d):GA690(r0-1780); GB 660(r60-1800); GC 840(r40-2840).Diuresis GA vs GC,P = 0.01.Leptin(ng/m L):GA vs GC,3.81(r0.78-69.60) vs GC,32.80(r0.78-124.50),P< 0.001.Insulin(μU/mL):GA vs GB,7(r2-44) vs 11.50(r4-38),P = 0.02; GA vs GC,7(r2-44) vs 19.5(r5-155),P = 0.0001.Troponin T and Pro-BNP levels were not different.Significant correlations:GC,Insulin-UF:ρ= 0.53; P = 0.03; Troponin T-diuresis:ρ =-0.48,P < 0.05; Pro-BNP-diuresis:ρ =-0.39,P < 0.01; Troponin T-ProB NP:ρ = 0.77,P < 0.0001; albumin-Troponin T:ρ =-0.66,P < 0.0001; albumin-ProB NP:ρ =-0.44,P < 0.05.CONCLUSION:High BMI associated positively with higher diuresis and albuminemia,and negatively with TropT and Pro-BNP.High BMI-associated better survival may be explained by better urinary output,lowering cardiovascular stress.