A novel approach to 4H-thieno[3,2-b]pyrroles

A novel approach to 4H-thieno[3,2-b]pyrroles

The condensation of 3-nitro-5-carboxy-2-methylthiophene with acetals of amides proceeds smoothly, and further ammonium formate-Pd/C reduction of nitroenamines thus obtained affords 2-carboxythieno-(5-R)-[3,2- b ]pyrroles (R = H, Me) in good yields.

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Bibliographic Details
Published in:Mendeleev communications Vol. 14; no. 1; p. 29
Main Authors: Krayushkin, Mikhail M, Stoyanovich, Felix M, Shorunov, Sergei V
Format: Journal Article
Language:English
Published: 01-01-2004
Online Access:Get full text
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Description
Summary:The condensation of 3-nitro-5-carboxy-2-methylthiophene with acetals of amides proceeds smoothly, and further ammonium formate-Pd/C reduction of nitroenamines thus obtained affords 2-carboxythieno-(5-R)-[3,2- b ]pyrroles (R = H, Me) in good yields.
ISSN:0959-9436
1364-557X
DOI:10.1070/MC2004v014n01ABEH001877