Risk of transferability and variable absorption of topical testosterone creams in children and adolescents

Key PointsTestosterone creams and gels (compared to topical patches or parenteral formulations) are associated with an increased risk of inadvertent transfer to close contact women and children, and thorough counselling on safe use in adult men and adolescent boys is critical to prevent this.Testost...

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Bibliographic Details
Published in:	Journal of paediatrics and child health Vol. 60; no. 2-3; pp. 69 - 72
Main Authors:	Vanderniet, Joel A, Neville, Kristen A
Format:	Journal Article
Language:	English
Published:	Australia Blackwell Publishing Ltd 01-02-2024
Subjects:	Endocrine therapy Human exposure Pediatrics Teenagers Testosterone Topical medication
Online Access:	Get full text
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Summary:	Key PointsTestosterone creams and gels (compared to topical patches or parenteral formulations) are associated with an increased risk of inadvertent transfer to close contact women and children, and thorough counselling on safe use in adult men and adolescent boys is critical to prevent this.Testosterone from topical preparations can remain in the skin for months after application, and sampling for serum testosterone should not occur through exposed skin.Close clinical and biochemical monitoring is required when using topical testosterone preparations for pubertal induction due to highly variable absorption and it is recommended that prescribing of testosterone preparations to children should be limited to endocrinologists.
ISSN:	1034-4810 1440-1754
DOI:	10.1111/jpc.16532