Intermediate scale for assessment of Parkinson's disease. Characteristics and structure

• Published in: Parkinsonism & related disorders Vol. 1; no. 2; pp. 97 - 102
• Main Authors: Martínez-Martin, P, Gil-Nagel, A, Morlán Gracia, L, Balseiro Gómez, J, Martínez-Sarriés, F.J, Bermejo, F, Del Ser Quijano, T, Macías, M.C, Jiménez-Rojas, C, Marañón, E, Grau Veciana, J.M, Roig Arnall, C, Bruna, O, JunquéPlaja, C, Giménez-Roldán, S, Burguera, J.A
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01-10-1995
• Subjects: Assessment; Intermediate Scale for Assessment of Parkinson's Disease (ISAPD); Parkinson's disease; Scales; Scales; Parkinson's disease; Intermediate Scale for Assessment of Parkinson's Disease (ISAPD); Assessment
• ISSN: 1353-8020; 1873-5126
• DOI: 10.1016/1353-8020(95)00002-X

The present study is devoted to the verification of the basic metrical characteristics of the ISAPD. One hundred and sixty-seven Parkinson's disease (PD) patients were included. Group A (
n = 40) was simultaneously assessed by five raters who applied the ISAPD and other PD rating scales (PDRS). A set of timed tests, the MiniMental State Examination (MMSE) and the Hamilton Scale for Depression (HSD) were administered by an independent examiner. Group B (
n = 127) was individually assessed through the UPDRS and the other PDRSs by separate neurologists in four different hospitals.
The ISAPD was administered in 7.0 ± 3.7 min. The internal consistency of this scale was high (Cronbach's alpha = 0.97). The inter-rater reliability of their items was very satisfactory (for all items, kappa > 0.70). There was a high correlation with the Hoehn and Yahr classification (
r
s = 0.71;
p < 0.001) and some timed tests. The convergent validity with the other PDRS (UPDRS and Schwab and England Scale) was also very high (
r
s = 0.83–0.92;
p < 0.001). The ISAPD also correlated with the MMSE and the HSD.
Factor analysis identified three factors (activities of daily living; gait and mobility; speech and eating) that explained 76% of the variance.
The ISAPD is an easy to apply, reliable, and valid scale that fulfills the aim for which it was designed.