Advances in biomathematical modeling for PET neuroreceptor imaging

Advances in biomathematical modeling for PET neuroreceptor imaging

The quantitative application of PET neuroreceptor imaging to study pathophysiology, diagnostics and drug development has continued to benefit from associated advances in biomathematical imaging methodology. We review some of these advances with particular focus on multi-modal image processing, trace...

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Bibliographic Details
Published in:Drug discovery today. Technologies Vol. 8; no. 2-4; pp. e45 - e51
Main Authors: Gunn, Roger N., Guo, Qi, Salinas, Cristian A., Tziortzi, Andri C., Searle, Graham E.
Format: Journal Article
Language:English
Published: England Elsevier Ltd 2011
Online Access:Get full text
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Summary:The quantitative application of PET neuroreceptor imaging to study pathophysiology, diagnostics and drug development has continued to benefit from associated advances in biomathematical imaging methodology. We review some of these advances with particular focus on multi-modal image processing, tracer kinetic modeling, occupancy studies and discovery and development of novel radioligands.
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ISSN:1740-6749
1740-6749
DOI:10.1016/j.ddtec.2012.01.001