Anti-Inflammatory and Antimicrobial Activity of Silver Nanoparticles Green-Synthesized Using Extracts of Different Plants

• Published in: Nanomaterials (Basel, Switzerland) Vol. 14; no. 17; p. 1383
• Main Authors: Mohamed, Amr, Dayo, Marwa, Alahmadi, Sana, Ali, Samah
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 25-08-2024
• Subjects: Adiantum capillus-veneris; Anti-inflammatory agents; anti-inflammatory and antimicrobial; Antimicrobial activity; Antimicrobial agents; Bacteria; Cichorium intybus; Denaturation; Fourier transforms; Ginkgo biloba; Gram-negative bacteria; Gram-positive bacteria; Inflammation; Infrared spectroscopy; Meloxicam; Methods; Microorganisms; Nanoparticles; Plant extracts; Rosmarinus officinalis; Scanning electron microscopy; Silver; silver nanoparticles; Surface plasmon resonance; Synthesis; Japan; Ginkgo biloba; Cichorium intybus; silver nanoparticles; anti-inflammatory and antimicrobial; Adiantum capillus-veneris; Rosmarinus officinalis
• ISSN: 2079-4991; 2079-4991
• DOI: 10.3390/nano14171383

In this study, an easy, efficient, economical, and eco-friendly green bio-synthesis method was utilized to synthesize silver nanoparticles (AgNPs) using the extracts of four plants:
,
,
, and
. The synthesis of AgNPs was confirmed by using a uv-vis spectrometer, which showed distinct surface plasmon resonance (SPR) bands. The surface of AgNPs was characterized using scanning electron microscopy and Fourier-transform infrared spectroscopy. The anti-inflammatory activity of Tenoxicam/Meloxicam-loaded AgNPs has been studied using the inhibition of albumin denaturation method. Tenoxicam-loaded AgNPs showed higher % Inhibition, but Meloxicam-loaded AgNPs showed lower % Inhibition. Furthermore, the AgNPs showed excellent antimicrobial activity on both Gram-negative and Gram-positive bacteria.