Antiretroviral therapy non-adherence and its association with psychosocial factors in Nigeria: comparative study of sexual minority and heterosexual men living with HIV

• Published in: AIDS care Vol. 36; no. 10; pp. 1369 - 1381
• Main Authors: Oginni, Olakunle Ayokunmi, Adelola, Aderopo Igbekeleoluwa, Ogunbajo, Adedotun, Opara, Onyedikachi Joseph, Akanji, Michael, Ibigbami, Olanrewaju Ibikunle, Afolabi, Olusegun Temitope, Akinsulore, Adesanmi, Mapayi, Boladale Moyosore, Mosaku, Samuel Kolawole
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis 02-10-2024; Taylor & Francis Ltd
• Subjects: Adherence; Adult; Anti-HIV Agents - therapeutic use; Antiretroviral agents; Antiretroviral therapy; ART non-adherence; Bisexuality; Comparative analysis; Comparative studies; Correlation; Cross-Sectional Studies; Depression - epidemiology; Depression - psychology; Heterosexuality; Heterosexuality - psychology; Heterosexuality - statistics & numerical data; HIV; HIV Infections - drug therapy; HIV Infections - psychology; Human immunodeficiency virus; Humans; Male; Medication Adherence - psychology; Medication Adherence - statistics & numerical data; Men who have sex with men; Mental depression; Mental health care; Mental health services; Middle Aged; Nigeria - epidemiology; Nigerian sexual minority men; Prescription drugs; Professional associations; psychosocial adversity; Psychosocial factors; Psychosocial support; Regression analysis; Regression models; SDG 10: Reduced inequalities; SDG 3: Good health and well-being; Self destructive behavior; Sexual and Gender Minorities - psychology; Sexual and Gender Minorities - statistics & numerical data; Sexually transmitted diseases; Social Stigma; Sociodemographics; STD; Stigma; Suicide; Surveys and Questionnaires; Young Adult; Nigeria; Nigerian sexual minority men; SDG 10: Reduced inequalities; HIV; ART non-adherence; SDG 3: Good health and well-being; psychosocial adversity
• ISSN: 0954-0121; 1360-0451; 1360-0451
• DOI: 10.1080/09540121.2024.2366511

Sexual minority men (gay, bisexual and other men who have sex with men; SMM) in Nigeria are disproportionately affected by HIV compared to heterosexual men. There is a dearth of research on the correlates of antiretroviral therapy (ART) non-adherence and correlates in both groups. The current study examined the associations of ART non-adherence with sociodemographic and psychosocial characteristics among a sample of Nigerian heterosexual and SMM. Between March and September 2014, we surveyed 120 SMM and 108 heterosexual men receiving ART in Lagos and Abuja, Nigeria. We specified univariate and multivariable linear regression models to examine correlates of ART non-adherence. We found that 50.8% and 29.6% of sexual minority and heterosexual men respectively self-reported ART non-adherence which was significantly associated with psychosocial factors such as stigma, depressive symptoms, and suicidality. Mental health care and psychosocial support should be incorporated into routine HIV care for Nigerian SMM living with HIV.