Anti-inflammatory Activity of Jurubeba (Solanum paniculatum L.) Through Reducing the T-bet and GATA3 Gene Expression, In Vitro

Anti-inflammatory Activity of Jurubeba (Solanum paniculatum L.) Through Reducing the T-bet and GATA3 Gene Expression, In Vitro

Furthermore, SpE at 60 μg/mL reduced the expression of T-bet (p <0.001), and at 30 and 60 μg/mL had attenuated GATA3 gene expression (p <0.01) in PWM-stimulated spleen cells.

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Bibliographic Details
Published in:Journal of allergy and clinical immunology Vol. 139; no. 2; p. AB268
Main Authors: Rios, Raimon, Ferreira Silva, Hugo Bernardino, Queiroz Carneiro, Norma Vilany, Costa, Ryan Santos, Brasil Carneiro, Tamires Cana, Marques, Cíntia Rodrigues, Serafim Machado, Marta Santos, Velozo, Eudes Silva, Silva, Telma M.G, Sarmento Silva, Tania Maria, Conceição, Adilva Souza, Alcântara-Neves, Neuza Maria, Figueiredo, Camila Alexandrina
Format: Journal Article
Language:English
Published: St. Louis Elsevier Inc 01-02-2017
Elsevier Limited
Subjects:
Allergy and Immunology
Gene expression
Rodents
Spleen
Online Access:Get full text
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Description
Summary:Furthermore, SpE at 60 μg/mL reduced the expression of T-bet (p <0.001), and at 30 and 60 μg/mL had attenuated GATA3 gene expression (p <0.01) in PWM-stimulated spleen cells.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2016.12.865