First report of bla GES-1 in Proteus mirabilis clinical isolates

Proteus mirabilis is one of the main pathogens causing urinary tract infections and sepsis. To our knowledge, this is the first report of a P. mirabilis hosting bla GES. The presence of these genes was determined using PCR and sequencing. We identified the presence of bla GES-1 in all three isolates...

Full description

Saved in:

Bibliographic Details
Published in:	Revista da Sociedade Brasileira de Medicina Tropical Vol. 54; p. e0864
Main Authors:	Beltrão, Elizabeth Maria Bispo, Oliveira, Érica Maria de, Lopes, Ana Catarina de Souza
Format:	Journal Article
Language:	English
Published:	Brazil Sociedade Brasileira de Medicina Tropical - SBMT 2021 Sociedade Brasileira de Medicina Tropical (SBMT)
Subjects:	Anti-Bacterial Agents beta-Lactamases - genetics bla GES bla NDM Case Report Enterobacteriaceae Microbial Sensitivity Tests Proteus mirabilis Proteus mirabilis - genetics TROPICAL MEDICINE bla GES Proteus mirabilis bla NDM
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	Proteus mirabilis is one of the main pathogens causing urinary tract infections and sepsis. To our knowledge, this is the first report of a P. mirabilis hosting bla GES. The presence of these genes was determined using PCR and sequencing. We identified the presence of bla GES-1 in all three isolates. In addition, we identified the bla KPC-2 and bla NDM-1 genes in the two strains. These data emphasize the importance of monitoring and surveillance of all enterobacteria. The circulation of P. mirabilis strains carrying bla GES-1 constitutes a new scenario of resistance in this species and should be an epidemiological alert for global health.
Bibliography:	Conflict of Interest: The authors declare that there is no conflict of interest. Authors' contribution: EMBB: Conception and design of the study, Conducting all laboratory experiments, writing the manuscript and reviewing the manuscript in English; EMO: Conception and design of the study, acquisition of data and English text review; ACSL: Conception and design of the study, data analysis, textual corrections of the manuscript and revision of the manuscript in English.
ISSN:	0037-8682 1678-9849 1678-9849
DOI:	10.1590/0037-8682-0864-2020