Emerging botanical processing technology of bioflavonoid for sustainable production of high value standardized nutraceutical ingredients: a review

• Published in: Journal of food measurement & characterization Vol. 18; no. 7; pp. 5602 - 5621
• Main Author: Che Zain, Mohamad Shazeli
• Format: Journal Article
• Language: English
• Published: New York Springer US 01-07-2024; Springer Nature B.V
• Subjects: Aging (natural); Bioactive compounds; Bioflavonoids; Biological activity; Chemistry; Chemistry and Materials Science; Chemistry/Food Science; Control equipment; Control methods; Diabetes mellitus; Effectiveness; Engineering; Flavonoids; Food Science; Functional foods & nutraceuticals; Herbal medicine; Medicinal plants; Pharmacology; Plant extracts; Polyphenols; Quality control; Review Paper; Standardization; Sustainable production; Technology assessment; Health benefit; Bioflavonoid; Standardization; Quality control; Omics
• ISSN: 2193-4126; 2193-4134
• DOI: 10.1007/s11694-024-02591-x

Herbal standardization is a crucial aspect in the field of herbal medicine and nutraceutical products. It refers to the process of developing and implementing standards to ensure the consistency, quality, and efficacy of herbal products. One important class of bioactive compounds that is widely distributed in plants is bioflavonoids, natural polyphenolic compounds. The significant pharmacological properties of bioflavonoids include antioxidant, anti-inflammatory, anti-diabetic, anti-aging and antimicrobial properties are promising therapeutic nutraceutical agents in the management of several acute and chronic diseases. However, the exploitation of these bioflavonoids demands systematic standardization approaches covering from extraction to enrichment of high-quality standardized multicomponent botanical extract in order to meet the desired efficacy. Hence, this review describes on the plant innovative processing technologies comprising of drying, solvent, extraction technique and adsorbent technologies accompanied with the established quality control methods using high end analytical instrument and omics technology. The importance of bioactive compound standardization and global demand of flavonoid in various applications are also highlighted.