Radiolytic Inactivation of Ponceau 4R Mutagenicity in Aqueous Solution

• Published in: High energy chemistry Vol. 57; no. 5; pp. 454 - 456
• Main Authors: Ponomarev, A. V., Kholodkova, E. M., Zotova, I. V., Shumega, A. R., Stepchenkova, E. I.
• Format: Journal Article
• Language: English
• Published: Moscow Pleiades Publishing 01-10-2023; Springer Nature B.V
• Subjects: Adducts; Aqueous solutions; Chemistry; Chemistry and Materials Science; Dyes; Electron beams; Genotoxicity; Mutagenicity; Physical Chemistry; Short Communications Radiation Chemistry; azo dye; mutagenicity; electron beam treatment; discoloration; Ponceau 4R
• ISSN: 0018-1439; 1608-3148
• DOI: 10.1134/S0018143923050119

The electron-beam treatment of an aqueous solution of the azo dye Ponceau 4R (0.02 g/dm
3
) at a dose of 1.5 kGy in air led to the complete elimination of color and genotoxicity. The addition of OH radicals to the system of conjugated bonds of the dye (the formation of OH adducts) was a key radiolytic process, which led to the elimination of side groups with lower binding energies.