Dermal Granuloma Annulare After SARS-CoV-2 Vaccination: A Rare Complication

Granuloma annulare (GA) is an inflammatory granulomatous skin disease of unknown etiology that is self-limiting in nature. However, it is hypothesized that trauma, medications, malignancy, viral infections, different vaccines, and hypersensitivity reactions can trigger the formation of GA. Only thre...

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Bibliographic Details
Published in:	Curēus (Palo Alto, CA) Vol. 16; no. 1; p. e52174
Main Authors:	Tahir, Muhammad, Bodies, Belin F, Shalin, Sara, Phung, Thuy, Myers, Thomas C, Israel, Robert, Piris, Adriano, Knowles, Kurt
Format:	Journal Article
Language:	English
Published:	United States Cureus Inc 12-01-2024 Cureus
Subjects:	Abdomen Acids Biopsy Collagen COVID-19 vaccines Cytokine storm Dermatology Drug dosages Females Granulomas Hospitals Immune system Internal Medicine Pathogenesis Pathology Patients Severe acute respiratory syndrome coronavirus 2 Skin Steroids Tumor necrosis factor-TNF White people United States > US covid-19 vaccine annular granuloma annulare post covid-19 vaccination interstitial granuloma annulare diffuse granuloma annulare granuloma annulare
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Description
Summary:	Granuloma annulare (GA) is an inflammatory granulomatous skin disease of unknown etiology that is self-limiting in nature. However, it is hypothesized that trauma, medications, malignancy, viral infections, different vaccines, and hypersensitivity reactions can trigger the formation of GA. Only three cases of post-SARS-CoV-2 vaccination-related GA have been reported so far. Here, we report the fourth documented case of post-SARS-CoV-2 vaccination-related generalized GA.
ISSN:	2168-8184 2168-8184
DOI:	10.7759/cureus.52174