A Rare Case of Laryngeal Osteosarcoma Causing Diagnostic Challenges

Laryngeal osteosarcomas are extremely rare. They cause diagnostic difficulty for the otolaryngologist and pathologist. Differentiation from sarcomatoid carcinoma is challenging but important, as clinical features and treatment strategies are different. Total laryngectomy is generally the preferred s...

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Bibliographic Details
Published in:	Curēus (Palo Alto, CA) Vol. 15; no. 4; p. e37393
Main Authors:	Kumbul, Yusuf Ç, Akın, Vural, Yasan, Hasan, Özdoğan Yılmaz, Gizem, Ayyıldız, Veysel A
Format:	Journal Article
Language:	English
Published:	United States Cureus Inc 10-04-2023 Cureus
Subjects:	Alcohol Biopsy Bone cancer Cartilage Case reports Chemotherapy Chronic obstructive pulmonary disease Cytokeratin Dyspnea Endoscopy Fibrosarcoma General anesthesia Hyperthyroidism Larynx Lymphatic system Medical diagnosis Metastasis Otolaryngology Pagets disease Pathology Radiation therapy Radiology Risk factors Sarcoma Smoking Thyroid gland histopathological examination laryngeal osteosarcomas sarcomatoid carcinomas diagnostic challenges total laryngectomy
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Summary:	Laryngeal osteosarcomas are extremely rare. They cause diagnostic difficulty for the otolaryngologist and pathologist. Differentiation from sarcomatoid carcinoma is challenging but important, as clinical features and treatment strategies are different. Total laryngectomy is generally the preferred surgical approach for laryngeal osteosarcomas. Since lymph node metastasis is not expected, neck dissection is not needed. In this report, we present a case diagnosed with laryngeal osteosarcoma post the examination of the total laryngectomy specimen of a laryngeal tumor that could not be histopathologically differentiated by punch biopsy.
ISSN:	2168-8184 2168-8184
DOI:	10.7759/cureus.37393