A Differential Clinical Diagnostic Challenge of a Recurrent, Oral Fibrosarcoma Resembling a Periapical Lesion of Endodontic Origin

A fibrosarcoma is a neoplastic growth originating from malignant, fibroblast-like mesenchymal cells. This malignant tumor shows an increased tendency for expansion and recurrence and a propensity to metastasize, especially to the lungs. Despite their rarity, fibrosarcomas have the potential to manif...

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Bibliographic Details
Published in:	Curēus (Palo Alto, CA) Vol. 15; no. 12; p. e49836
Main Authors:	Zisis, Vasileios, Poulopoulos, Athanasios, Fotopoulos, Ioannis, Lillis, Theodoros, Dabarakis, Nikolaos, Anagnostou, Eleftherios, Andreadis, Dimitrios
Format:	Journal Article
Language:	English
Published:	United States Cureus Inc 02-12-2023 Cureus
Subjects:	Biopsy Chemotherapy Dentistry Disease Fibroblasts Fibrosarcoma Granulomas Head & neck cancer Medical diagnosis Medical prognosis Oncology Oral Medicine Pathology Sarcoma Tumors head and neck neoplasms oral diseases recurrent sarcoma immunohistochemistry staining fibrosarcoma
Online Access:	Get full text
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Summary:	A fibrosarcoma is a neoplastic growth originating from malignant, fibroblast-like mesenchymal cells. This malignant tumor shows an increased tendency for expansion and recurrence and a propensity to metastasize, especially to the lungs. Despite their rarity, fibrosarcomas have the potential to manifest in any anatomical location. An oncologist referred their patient due to reported mandibular discomfort, ache, and swelling. The biopsy revealed a fibrosarcoma resembling a periapical lesion of endodontic origin. The timely intervention and the collaboration among different but complementary medical and dental specialties ensure that the patient may enjoy a prolonged life expectancy as symptom-free as possible.
ISSN:	2168-8184 2168-8184
DOI:	10.7759/cureus.49836