Validation of the Spanish version of Addenbrooke's Cognitive Examination III for diagnosing dementia

Addenbrooke's Cognitive Examination is a screening test used to diagnose dementia. The third edition of this test (ACE-III) was recently developed. The aim of this study was to translate and validate the ACE-III in Spanish. The ACE-III was translated and adapted to Spanish. It was then administ...

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Bibliographic Details
Published in:Neurología (Barcelona, English ed. ) Vol. 30; no. 9; pp. 545 - 551
Main Authors: Matias-Guiu, J.A., Fernández de Bobadilla, R., Escudero, G., Pérez-Pérez, J., Cortés, A., Morenas-Rodríguez, E., Valles-Salgado, M., Moreno-Ramos, T., Kulisevsky, J., Matías-Guiu, J.
Format: Journal Article
Language:English
Published: Elsevier España, S.L.U 01-11-2015
Elsevier España
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Summary:Addenbrooke's Cognitive Examination is a screening test used to diagnose dementia. The third edition of this test (ACE-III) was recently developed. The aim of this study was to translate and validate the ACE-III in Spanish. The ACE-III was translated and adapted to Spanish. It was then administered to a group of healthy subjects as well as a group of patients with different types of mild dementia treated in 2 hospitals in Spain. Internal reliability (Cronbach's alpha=0.927), inter-rater reliability (intraclass correlation coefficient=0.976) and test–retest reliability (kappa 0.995) were excellent. Age (r=−0.512) and education (r=0.659) showed a significant correlation with total test scores. The diagnostic accuracy of ACE-III was higher than that of the Mini-Mental State Examination, particularly for the group with the highest educational level. Researchers obtained normative data and cut-off points for the diagnosis of dementia. The Spanish version of the ACE-III is a reliable and valid test for diagnosing dementia. Its diagnostic accuracy is high, especially in patients with a higher level of education. El Addenbrooke's Cognitive Examination (ACE) es un test de cribado para el diagnóstico de demencia. Recientemente, se ha desarrollado la tercera versión del test (ACE-III). El objetivo del estudio fue la traducción y adaptación del ACE-III al español y su validación. El ACE-III fue traducido y adaptado al español. Se administró a un grupo de sujetos cognitivamente sanos y a pacientes con demencia leve de diferentes tipos en 2 centros españoles. La consistencia interna del test (alfa de Cronbach=0,927), la fiabilidad interevaluador (coeficiente de correlación intraclase=0,976) y la fiabilidad test-retest (kappa=0,995) fueron elevadas. Edad (r=−0,512) y escolaridad (r=0,659) se correlacionaron significativamente con la puntuación total del test. La capacidad diagnóstica del ACE-III fue superior al Mini-Mental State Examination, especialmente en el grupo con mayor escolaridad. Se obtuvieron datos normativos por edad, y puntos de corte para la detección de demencia. La versión española del test ACE-III es un instrumento válido para el diagnóstico de demencia, con una alta capacidad discriminatoria especialmente en pacientes con un mayor nivel educativo.
ISSN:2173-5808
2173-5808
DOI:10.1016/j.nrleng.2014.05.001