Diverticular disease as a chronic gastrointestinal condition: experience from a specialist clinic

• Published in: European journal of gastroenterology & hepatology Vol. 27; no. 4; pp. 442 - 448
• Main Authors: Kvasnovsky, Charlotte L, Adams, Katie, Papagrigoriadis, Savvas
• Format: Journal Article
• Language: English
• Published: England 01-04-2015
• Subjects: Adult; Aged; Chronic Disease; Diverticulitis, Colonic - diagnosis; Diverticulitis, Colonic - etiology; Diverticulitis, Colonic - surgery; Female; Humans; Logistic Models; Male; Medical Audit; Middle Aged; Referral and Consultation - statistics & numerical data; Retrospective Studies; Risk Factors
• ISSN: 0954-691X; 1473-5687
• DOI: 10.1097/MEG.0000000000000304

Although diverticular disease is a prevalent condition and a significant burden on the healthcare system, care is devolved across gastrointestinal, GP, and colorectal surgery clinics. We created a specialist Diverticular Disease Clinic to streamline care, enhance evidence-based practice and provide a base for research. The aim of this study was to assess patient referral sources, predictors of persistent disease and surgical outcomes.
We retrospectively reviewed all patients attending our clinic. Patients younger than 50 years of age on initial presentation were considered 'younger' patients. Persistent symptoms lasted for at least 3 months.
Overall, 177 patients had confirmed diverticular disease. Patients were referred following hospital admission (82 patients, 46.3%) or from the community (95 patients, 53.7%). Ninety-five patients (53.7%) had persistent symptoms. Patients with more than two episodes of diverticulitis were more likely to have persistent symptoms (P<0.0001).Following hospitalization, younger patients were 3.98 times more likely to develop persistent symptoms (P=0.04). This was independent of the severity of the original infection, as a low peak C-reactive protein level of less than 50 mg/L was associated with persistent symptoms (odds ratio=3.62, P=0.03). Over the study period, 12 patients (6.9%) had elective surgery.
There is demand for dedicated care for patients with persistent symptoms from diverticular disease. Specialized clinics are a model for this care, provided by either gastroenterologists or surgeons, in centres with adequate demand. Our findings reinforce the hypotheses that chronic abdominal pain in diverticular disease may be related to sensation abnormalities similar to postinfective irritable bowel syndrome.