Neonatal complicated intraabdominal infection

The purpose of this review is to summarize the treatment of complicated intraabdominal infections (cIAIs) in premature infants. Recent work has continued to define the complex nature of cIAIs and necrotizing enterocolitis (NEC). This includes new findings on the microbiome, breast milk and risk fact...

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Bibliographic Details
Published in:Current opinion in infectious diseases Vol. 36; no. 5; pp. 414 - 419
Main Authors: Rauh, Jessica L, Lehane, Alison J, Sieren, Leah M, Neff, Lucas P
Format: Journal Article
Language:English
Published: United States 01-10-2023
Online Access:Get full text
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Summary:The purpose of this review is to summarize the treatment of complicated intraabdominal infections (cIAIs) in premature infants. Recent work has continued to define the complex nature of cIAIs and necrotizing enterocolitis (NEC). This includes new findings on the microbiome, breast milk and risk factors associated with NEC. The treatment of cIAIs employs a combination of both surgical and medical treatment. Further look at what type and timing of surgical intervention is used as well as the ideal antibiotic regimen. Upcoming research is highlighted in future directions of NEC treatment. cIAIs in premature infants is a challenging disease with more research needed to further delineate the pathophysiology and treatment options.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
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ObjectType-Review-1
ISSN:0951-7375
1473-6527
DOI:10.1097/QCO.0000000000000950