Mycoplasma pneumoniae-induced rash and mucositis: A new entity

• Published in: Indian journal of dermatology, venereology, and leprology Vol. 88; no. 3; pp. 349 - 353
• Main Authors: Ben Rejeb, Mohamed, Ben Hammouda, Mouna, Korbi, Mouna, Belhadjali, Hichem, Toumi, Adnene, Youssef, Monia, Zili, Jameleddine
• Format: Journal Article
• Language: English
• Published: United States 01-05-2022
• Subjects: Mycoplasma pneumoniae; Stevens-Johnson syndrome; mucositis; Erythema multiforme
• ISSN: 0378-6323; 0973-3922
• DOI: 10.25259/IJDVL_660_19

Mycoplasma pneumoniae is a well-known cause of community-acquired pneumonia, mostly associated with dermatological manifestations especially with mucosal involvement and targetoid cutaneous lesions. For many years, it was considered among the spectrum of erythema multiforme. Recently, some authors have recommended the creation of a new syndrome called "mycoplasma-induced rash and mucositis." This new syndrome has distinct epidemiological, clinical and histological features making it different from drug-induced Stevens-Johnson syndrome, toxic epidermal necrosis and erythema multiforme. Herein, we report two patients with acute Mycoplasma pneumoniae respiratory tract infection presenting severe mucocutaneous lesions in accordance with this new syndrome.