Fractional Flow Reserve–Based Coronary Artery Bypass Surgery

• Published in: JACC. Cardiovascular interventions Vol. 13; no. 9; pp. 1086 - 1096
• Main Authors: Spadaccio, Cristiano, Glineur, David, Barbato, Emanuele, Di Franco, Antonino, Oldroyd, Keith G., Biondi-Zoccai, Giuseppe, Crea, Filippo, Fremes, Stephen E., Angiolillo, Dominick J., Gaudino, Mario
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 01-05-2020
• Subjects: CABG; FFR; myocardial revascularization; myocardial revascularization; FFR; SVG; CI; ITA; PCI; LITA; PRISMA; HR; CABG; LAD; RA
• ISSN: 1936-8798; 1876-7605
• DOI: 10.1016/j.jcin.2019.12.017

Fractional flow reserve (FFR) provides an objective measurement of the severity of ischemia caused by coronary stenoses in downstream myocardial regions. Data from the interventional cardiology realm have suggested benefits of a FFR-guided percutaneous coronary intervention (PCI) strategy. Limited evidence is available on the use of FFR to guide coronary artery bypass grafting (CABG). The most recent data have shown that FFR might simplify CABG procedures and optimize patency of arterial grafts without any clear impact on clinical outcomes. The aim of this review was to summarize the available data on FFR-based CABG and discuss the rationale and potential consequences of a switch toward FFR-based surgical revascularization strategy.
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