Diagnostic markers for glioblastoma
Glioblastoma (GBM) is the most malignant form of cerebral gliomas, and despite distinct progress in surgical resection, radiation and chemotherapy, the prognosis of patients with GBM is still very poor. In the past decades knowledge of genomics and proteomics and of diagnostic, prognostic, predictiv...
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| Published in: | Histology and histopathology Vol. 26; no. 10; pp. 1327 - 1341 |
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| Main Authors: | , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
Spain
01-10-2011
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| Online Access: | Get full text |
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| Abstract | Glioblastoma (GBM) is the most malignant form of cerebral gliomas, and despite distinct progress in surgical resection, radiation and chemotherapy, the prognosis of patients with GBM is still very poor. In the past decades knowledge of genomics and proteomics and of diagnostic, prognostic, predictive and pharmakodynamic markers measured in cerebrospinal-fluid (CSF), serum, or tumor tissue biomarkers has improved. This review briefly compiles our concepts on diagnostic markers for GBM, focusing on the latest developments. |
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| AbstractList | Glioblastoma (GBM) is the most malignant form of cerebral gliomas, and despite distinct progress in surgical resection, radiation and chemotherapy, the prognosis of patients with GBM is still very poor. In the past decades knowledge of genomics and proteomics and of diagnostic, prognostic, predictive and pharmakodynamic markers measured in cerebrospinal-fluid (CSF), serum, or tumor tissue biomarkers has improved. This review briefly compiles our concepts on diagnostic markers for GBM, focusing on the latest developments. |
| Author | Unterberg, A W Hartmann, C Jung, C S |
| Author_xml | – sequence: 1 givenname: C S surname: Jung fullname: Jung, C S email: carla.jung@med.uni-heidelberg.de organization: Department of Neurosurgery, Institute of Pathology, Ruprecht-Karls-University Heidelberg and Clinical Cooperation Unit Neuropathology, German Cancer Research Center, Germany. carla.jung@med.uni-heidelberg.de – sequence: 2 givenname: A W surname: Unterberg fullname: Unterberg, A W – sequence: 3 givenname: C surname: Hartmann fullname: Hartmann, C |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/21870336$$D View this record in MEDLINE/PubMed |
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| SubjectTerms | Biomarkers, Tumor - analysis Brain Neoplasms - diagnosis Brain Neoplasms - metabolism Glioblastoma - diagnosis Glioblastoma - metabolism Humans |
| Title | Diagnostic markers for glioblastoma |
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