Diagnostic markers for glioblastoma

Glioblastoma (GBM) is the most malignant form of cerebral gliomas, and despite distinct progress in surgical resection, radiation and chemotherapy, the prognosis of patients with GBM is still very poor. In the past decades knowledge of genomics and proteomics and of diagnostic, prognostic, predictiv...

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Bibliographic Details
Published in:	Histology and histopathology Vol. 26; no. 10; pp. 1327 - 1341
Main Authors:	Jung, C S, Unterberg, A W, Hartmann, C
Format:	Journal Article
Language:	English
Published:	Spain 01-10-2011
Subjects:	Biomarkers, Tumor - analysis Brain Neoplasms - diagnosis Brain Neoplasms - metabolism Glioblastoma - diagnosis Glioblastoma - metabolism Humans
Online Access:	Get full text
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Summary:	Glioblastoma (GBM) is the most malignant form of cerebral gliomas, and despite distinct progress in surgical resection, radiation and chemotherapy, the prognosis of patients with GBM is still very poor. In the past decades knowledge of genomics and proteomics and of diagnostic, prognostic, predictive and pharmakodynamic markers measured in cerebrospinal-fluid (CSF), serum, or tumor tissue biomarkers has improved. This review briefly compiles our concepts on diagnostic markers for GBM, focusing on the latest developments.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1
ISSN:	1699-5848
DOI:	10.14670/HH-26.1327