Novel Use of Wound Matrix in Mastopexy Complicated by Pyoderma Gangrenosum

Novel Use of Wound Matrix in Mastopexy Complicated by Pyoderma Gangrenosum

Abstract   Pyoderma gangrenosum (PG) is a relatively uncommon inflammatory skin disorder that is characterized by rapid onset, ulcerative lesions, and often triggered by trauma or surgery. Although rare, PG of the breast has been well described in the plastic surgery literature, most often reported...

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Bibliographic Details
Published in:Aesthetic surgery journal. Open forum Vol. 5
Main Authors: Ragsdale, Louisa B, Sarhaddi, Deniz, Nathan, Charles
Format: Journal Article
Language:English
Published: US Oxford University Press 11-01-2023
Subjects:
Case Report
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Summary:Abstract   Pyoderma gangrenosum (PG) is a relatively uncommon inflammatory skin disorder that is characterized by rapid onset, ulcerative lesions, and often triggered by trauma or surgery. Although rare, PG of the breast has been well described in the plastic surgery literature, most often reported following breast reductions and reconstructions. The authors present a case of PG that developed in a 56-year-old patient, with a history of essential thrombocytosis, following mastopexy. Her significant full-thickness skin loss was successfully treated with steroids and then reconstructed via serial applications of porcine placental extracellular matrix grafts. Her wounds were completely healed in 3.5 months for the left, and 5 months for the right breast. To the best of the author's knowledge, this is the first published case in which placental grafts have been successfully used to reconstruct pyoderma wounds of the breast. Given their advantageous scarring and lack of donor-site morbidity, placental grafts should be considered for all breast surgery patients afflicted by PG. Level of Evidence: 5
Bibliography:Dr Ragsdale is a plastic surgery resident, Division of Plastic and Reconstructive Surgery, Saint Louis University School of Medicine, Saint Louis, MO, USA.
Dr Sarhaddi is a next generation editor for Aesthetic Surgery Journal, and an oculoplastic surgery section contributing editor for ASJ Open Forum.
Drs Sarhaddi and Nathan are board-certified plastic surgeons in private practice in Chesterfield, MO, USA.
ISSN:2631-4797
2631-4797
DOI:10.1093/asjof/ojad085