Dextrorphan-binding proteins in the hippocampus of audiosensitized rats genetically predisposed to epilepsy

Dextrorphan-binding proteins in the hippocampus of audiosensitized rats genetically predisposed to epilepsy

A fraction of dextrorphan-binding proteins is isolated from the hippocampus of normal and audiosensitized Krushinsky-Molodkina rats genetically predisposed to epilepsy. Pharmacological analysis of this fraction reveals the presence of haloperidol-sensitive phencyclidine- (N-[1-Phenylcyclohexyl]piper...

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Bibliographic Details
Published in:Bulletin of experimental biology and medicine Vol. 124; no. 2; pp. 770 - 772
Main Authors: Natsvlishvili, N. I., Abutidze, K. D., Mikeladze, D. G.
Format: Journal Article
Language:English
Published: New York Springer Nature B.V 01-08-1997
Subjects:
Chromatography
Molecular weight
Proteins
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Summary:A fraction of dextrorphan-binding proteins is isolated from the hippocampus of normal and audiosensitized Krushinsky-Molodkina rats genetically predisposed to epilepsy. Pharmacological analysis of this fraction reveals the presence of haloperidol-sensitive phencyclidine- (N-[1-Phenylcyclohexyl]piperidine, PCP)-binding proteins with molecular weight 18-20 kD judging from the data of high-performance liquid chromatography.[PUBLICATION ABSTRACT]
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
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ISSN:0007-4888
1573-8221
DOI:10.1007/BF02445087