Surgical management of brain metastases

• Published in: Neurosurgical focus Vol. 22; no. 3; pp. E2 - 7
• Main Authors: Ranasinghe, Moksha G, Sheehan, Jonas M
• Format: Journal Article
• Language: English
• Published: United States 15-03-2007
• Subjects: Brain Neoplasms - radiotherapy; Brain Neoplasms - secondary; Brain Neoplasms - surgery; Humans; Neoplasm Metastasis - therapy; Neurosurgical Procedures - standards; Neurosurgical Procedures - statistics & numerical data; Patient Selection; Postoperative Care - standards; Postoperative Complications - etiology; Postoperative Complications - physiopathology; Radiotherapy - standards; Radiotherapy - statistics & numerical data; Survival Rate - trends; Treatment Outcome
• ISSN: 1092-0684; 1092-0684
• DOI: 10.3171/foc.2007.22.3.3

Metastatic brain tumors continue to increase in incidence as patients with cancer live longer. The options for management continue to evolve as well, with advances in radiation-based treatment, chemotherapy, and surgery. Although metastatic brain tumors are frequently treated without surgical intervention, there continues to be a significant role for surgery in caring for patients with these lesions. Study data have proven that surgery has a positive effect on survival and quality of life in properly selected patients. Those with a suitable age, functional status, systemic disease control, and several metastases may be suitable for surgical treatment. Advances in preoperative imaging and planning as well as intraoperative surgical adjuncts have lowered the morbidity associated with resection. With proper patient selection and operative and postoperative management, resection continues to play a significant and evolving role in the care of patients with metastatic brain tumor.