Erdheim–Chester disease with cardiac involvement. Case report

ErdheimChester disease (ECD) is a rare non-Langerhans histiocytosis with multisystem inflammatory infiltrates consistent of monocytes/macrophages, reactive microenvironment and fibrotic fields. Cardiovascular involvement is one of the most frequent manifestations of ECD that can lead to life threati...

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Bibliographic Details
Published in:	Terapevtic̆eskii arhiv Vol. 94; no. 7; pp. 897 - 902
Main Authors:	Latyshev, Vitalii D., Mershina, Elena А., Kostina, Irina E., Sinitsyn, Valentin Е., Lukina, Elena A.
Format:	Journal Article
Language:	English Russian
Published:	"Consilium Medicum" Publishing house 12-08-2022
Subjects:	erdheim–chester disease mutation braf v600e non-langerhans cell histiocytosis trametinib
Online Access:	Get full text
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Summary:	ErdheimChester disease (ECD) is a rare non-Langerhans histiocytosis with multisystem inflammatory infiltrates consistent of monocytes/macrophages, reactive microenvironment and fibrotic fields. Cardiovascular involvement is one of the most frequent manifestations of ECD that can lead to life threating complications. In this article we are reporting a clinical case of ECD with cardiac involvement in a young patient.
ISSN:	0040-3660 2309-5342
DOI:	10.26442/00403660.2022.07.201737