Management of ruptured retinal arterial macroaneurysm with intravitreal bevacizumab

• Published in: Ophthalmic surgery, lasers & imaging Vol. 41 Online; p. e1
• Main Authors: Javey, Golnaz, Moshfeghi, Arlanna N, Moshfeghi, Andrew A
• Format: Journal Article
• Language: English
• Published: United States 30-08-2010
• Subjects: Aged; Aneurysm, Ruptured - complications; Aneurysm, Ruptured - diagnosis; Aneurysm, Ruptured - drug therapy; Aneurysm, Ruptured - physiopathology; Antibodies, Monoclonal - administration & dosage; Antibodies, Monoclonal, Humanized; Bevacizumab; Drug Administration Schedule; Female; Fundus Oculi; Humans; Intravitreal Injections; Retinal Artery; Retinal Hemorrhage - etiology; Retinal Hemorrhage - physiopathology; Tomography, Optical Coherence; Treatment Outcome; Ultrasonography; Visual Acuity - drug effects
• ISSN: 1938-2375
• DOI: 10.3928/15428877-20100830-07

The authors report the management of a ruptured retinal arterial macroaneurysm and associated hemorrhages with intravitreal injections of bevacizumab. A 79-year-old woman presented with a history of systemic arterial hypertension and a ruptured retinal arterial macroaneurysm with pre-retinal, intraretinal, and subretinal hemorrhages extending into the macula. Visual acuity at presentation was 20/400. The patient was treated with two intravitreal injections of bevacizumab at 4-week intervals. Steady clearing of the pre-retinal, intraretinal, and subretinal hemorrhages was observed with restoration of final visual acuity to 20/20 in the 12 months after the initial presentation. It appears that the novel application of intravitreal bevacizumab may be used in the treatment of ruptured retinal arterial macroaneurysm.