Myelin oligodendrocyte glycoprotein antibody–associated disease with histopathologic features of primary CNS angiitis without demyelination: Case report and literature review

Primary angiitis of the central nervous system (PACNS) is a rare inflammatory disease that affects both small- and medium-sized vessels of the CNS, while myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD) is a novel antibody-mediated inflammatory demyelinating disorder tha...

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Bibliographic Details
Published in:	Journal of neuroimmunology Vol. 396; p. 578467
Main Authors:	Kim, Seongmi, Lee, Suin, Chung, Yeon Hak, Ju, Hyunjin, Suh, Yeon-Lim, Min, Ju-Hong
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 15-11-2024
Subjects:	Brain biopsy MOGAD Myelin oligodendrocyte glycoprotein Primary angiitis of the central nervous system Primary angiitis of the central nervous system Brain biopsy MOGAD Myelin oligodendrocyte glycoprotein
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Summary:	Primary angiitis of the central nervous system (PACNS) is a rare inflammatory disease that affects both small- and medium-sized vessels of the CNS, while myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD) is a novel antibody-mediated inflammatory demyelinating disorder that causes damage to the myelin in CNS. We report a case diagnosed as MOGAD due to a history of recurrent myelitis, brain lesions, and positive anti-MOG, but the brain biopsy showed vasculitis without demyelination.
Bibliography:	ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Review-5 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3
ISSN:	0165-5728 1872-8421 1872-8421
DOI:	10.1016/j.jneuroim.2024.578467