The architecture of paranoia in the general population: A self-report and ecological momentary assessment study

• Published in: Schizophrenia research Vol. 271; pp. 206 - 219
• Main Authors: Neidhart, Maja, Mohnke, Sebastian, Vogel, Bob O., Walter, Henrik
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01-09-2024
• Subjects: Adolescent; Adult; Aged; Continuum; Cross-Sectional Studies; Delusion; Ecological Momentary Assessment; Etiology; Female; Germany - epidemiology; Hierarchy; Humans; Longitudinal Studies; Male; Middle Aged; Paranoia; Paranoid Disorders - epidemiology; Self Report; Severity subgroups; Young Adult; Germany; Continuum; Delusion; Hierarchy; Paranoia; Severity subgroups; Etiology
• ISSN: 0920-9964; 1573-2509; 1573-2509
• DOI: 10.1016/j.schres.2024.07.021

Paranoia is a common delusion type found in clinical and non-clinical populations. A hierarchical, dimensional model of paranoia in the general population has been proposed, with four categories representing increasing levels of paranoia: interpersonal sensitivity (IP), mistrust (M), ideas of reference (IR), persecutory ideas (PI). What is currently lacking and could provide insights into etiology is a comprehensive clinical characterization of the lower end of the paranoia spectrum, psychological domains that are associated with symptom severity, and how paranoia and its structure fluctuate over time. This study conducted both cross-sectional and longitudinal surveys with 802 participants from the German population assessing paranoia and general psychopathology. Data was collected through Ecological Momentary Assessment (EMA). Several statistical approaches were used including confirmatory factor analysis (CFA), latent class analysis (LCA) and mixed modelling analyses (ME). Paranoid experiences appear to be a common phenomenon that occur in people with and without mental illness. Subjects clustered into four paranoia severity subgroups (IP, M, IR, PI) and showed significant associations in various psychological domains like increased psychiatric symptoms and maladaptive coping. Paranoia fluctuates over time in all four severity subgroups, but the hierarchical subgrouping was stable. Both persecutory ideations and interpersonal sensitivity were significant predictors of paranoia. Findings provide important insights into the architecture of paranoia in the German population by characterizing their hierarchical, dimensional, and dynamic structure and its link to psychopathology.