3-Hydroxyneocryptolepine, a new indoloquinoline alkaloid from the roots of Cryptolepis sanguinolenta (Lindl.) Schltr
Phytochemical investigations of the African ethnomedicinal plant (Lindl.) Schltr. (Apocynaceae) have yielded only a small number of rare naturally occurring indoloquinoline alkaloids. Our recent work has resulted in the isolation of a new indoloquinoline named 3-hydroxyneocryptolepine, which was obt...
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| Published in: | Natural product research pp. 1 - 6 |
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| Main Authors: | , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
England
27-07-2024
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| Subjects: | |
| Online Access: | Get full text |
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| Summary: | Phytochemical investigations of the African ethnomedicinal plant
(Lindl.) Schltr. (Apocynaceae) have yielded only a small number of rare naturally occurring indoloquinoline alkaloids. Our recent work has resulted in the isolation of a new indoloquinoline named 3-hydroxyneocryptolepine, which was obtained from an ethanolic extract of the roots. The structure of the compound was elucidated based on 1D and 2D NMR as well as HRESIMS spectral evidence. LDL uptake promotion activity of the compound in HepG2 cells was not significant. |
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| Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| ISSN: | 1478-6419 1478-6427 1478-6427 |
| DOI: | 10.1080/14786419.2024.2383995 |