Creating Tubular Structures from Tissue Spheroids via the Acoustic Radiation Force

Creating Tubular Structures from Tissue Spheroids via the Acoustic Radiation Force

A method is proposed of fabricating tubular constructs from tissue spheroids (conglomerates of cells up to 200 μm in size) in a nutrient fluid using the acoustic radiation force. The source of the acoustic field is a hollow piezoceramic cylinder with a resonant frequency of 800 kHz. Keeping the obta...

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Bibliographic Details
Published in:Bulletin of the Russian Academy of Sciences. Physics Vol. 85; no. 6; pp. 681 - 685
Main Authors: Krokhmal, A. A., Sapozhnikov, O. A., Koudan, E. V., Gryadunova, A. A., Tsysar, S. A., Petrov, C. V., Pereira, F., Hesuani, Y. D., Mironov, V. A., Parfenov, V. A.
Format: Journal Article
Language:English
Published: Moscow Pleiades Publishing 01-06-2021
Springer Nature B.V
Subjects:
Acoustics
Hadrons
Heavy Ions
Nuclear Physics
Physics
Physics and Astronomy
Radiation
Resonant frequencies
Sound waves
Spheroids
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Summary:A method is proposed of fabricating tubular constructs from tissue spheroids (conglomerates of cells up to 200 μm in size) in a nutrient fluid using the acoustic radiation force. The source of the acoustic field is a hollow piezoceramic cylinder with a resonant frequency of 800 kHz. Keeping the obtained structure at 37°C for 24 h fuses the spheroids into a solid tubular viable tissue construct.
ISSN:1062-8738
1934-9432
DOI:10.3103/S1062873821060137