Digestive disorders and Intestinal microbiota

• Published in: Acta bio-medica : Atenei Parmensis Vol. 89; no. 9-S; pp. 47 - 51
• Main Authors: Nouvenne, Antonio, Ticinesi, Andrea, Tana, Claudio, Prati, Beatrice, Catania, Pamela, Miraglia, Chiara, De' Angelis, Gian Luigi, Di Mario, Francesco, Meschi, Tiziana
• Format: Journal Article
• Language: English
• Published: Italy Mattioli 1885 17-12-2018
• Subjects: Biodiversity; Celiac Disease - microbiology; Clostridium difficile; Clostridium Infections - microbiology; Digestive System Diseases - etiology; Digestive System Diseases - microbiology; Digestive System Neoplasms - etiology; Digestive System Neoplasms - microbiology; Disease Susceptibility; Dysbiosis - complications; Dysbiosis - therapy; Endotoxins - metabolism; Gastrointestinal Microbiome; Humans; Inflammatory Bowel Diseases - microbiology; Intestinal Absorption; Irritable Bowel Syndrome - microbiology; Irritable Bowel Syndrome - physiopathology; Liver Diseases - microbiology; Review
• ISSN: 0392-4203; 2531-6745
• DOI: 10.23750/abm.v89i9-S.7912

In the last decade, a barge body of scientific literature has suggested that specific alterations of the gut microbiota may be associated with ther development and clinical course of several gastrointestinal diseases, including irritable bowel syndrome, inflammatory bowel disease, celiac disease, gastrointestinal cancer and Clostridium difficile infection. These alterations are often referred to as "dysbiosis", a generic term designing reduction of gut microbiota biodiversity and alterations in its composition. Here, we provide a synthetic overview of the key concepts on the relationship between intestinal microbiota and gastrointestinal diseases, focusing on the translation of these concepts into clinical practice.