Characterization of alpha-adrenergic receptors in guinea pig cerebral cortex: effect of chronic antidepressant treatments

Alpha-adrenergic receptor sites in cerebral cortex membranes of the guinea pig have been characterized by the specific binding of 3H-WB4101, an alpha-adrenergic antagonist. The binding was rapid, reversible, saturable, and stereoselective. The maximal binding site (Bmax) and dissociation constant (k...

Full description

Bibliographic Details

Published in:	Psychopharmacology Vol. 74; no. 3; pp. 201 - 203
Main Authors:	Hu, H Y, Davis, J M, Pandey, G N
Format:	Journal Article
Language:	English
Published:	Germany 1981
Subjects:	Adrenergic alpha-Agonists - pharmacology Adrenergic alpha-Antagonists - pharmacology Animals Antidepressive Agents - pharmacology Binding, Competitive Cerebral Cortex - drug effects Dioxanes Guinea Pigs Male Receptors, Adrenergic - drug effects Receptors, Adrenergic, alpha - drug effects
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!