Genetically Based Resistance to the Development of Allergen-induced Asthma is Associated With Robust Plasmacytoid DC Recruitment and Activation

Results Flow cytometric analysis of pulmonary and LN DC populations revealed that while HDM exposure induced mDC recruitment in both strains, the magnitude of increase was greater in A/J than C3H mice. [...]in A/J mice, a greater percentage of mDCs were positive for allergen, and simultaneously expr...

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Bibliographic Details
Published in:	Journal of allergy and clinical immunology Vol. 121; no. 2; p. S133
Main Authors:	Lewkowich, I.P, Clark, J.C, Schleifer, K.W, Sproles, A.A, Wills-Karp, M
Format:	Journal Article
Language:	English
Published:	St. Louis Mosby, Inc 01-02-2008 Elsevier Limited
Subjects:	Allergies Allergy and Immunology Asthma Recruitment
Online Access:	Get full text
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Summary:	Results Flow cytometric analysis of pulmonary and LN DC populations revealed that while HDM exposure induced mDC recruitment in both strains, the magnitude of increase was greater in A/J than C3H mice. [...]in A/J mice, a greater percentage of mDCs were positive for allergen, and simultaneously expressed MHC Class II and CD86.
ISSN:	0091-6749 1097-6825
DOI:	10.1016/j.jaci.2007.12.531