Severe Mitral Valve Regurgitation Secondary to Fulminant Myocarditis in the Setting of a Lupus Flare

• Published in: Journal of community hospital internal medicine perspectives Vol. 14; no. 3; p. 81
• Main Authors: Romero, Jesus, Elkattawy, Sherif, Abboud, Rachel, Masood, Abdullah, Jawed, Qirat, Romero, Ana L, Fichadiya, Hardik A, Abu-Samak, Abdel-Azez, Shamoon, Yezin F, Elkattawy, Omar, Joshi, Meherwan, Shamoon, Fayez E
• Format: Journal Article
• Language: English
• Published: United States 07-05-2024
• Subjects: Impella; Endomyocardial biopsy; Cardiogenic shock; Lupus myocarditis; Cardiac magnetic resonance; VA-ECMO
• ISSN: 2000-9666; 2000-9666
• DOI: 10.55729/2000-9666.1336

Systemic Lupus Erythematosus represents a chronic autoimmune disorder characterized by multiorgan involvement. Lupus myocarditis is a rare presentation of one of the cardiac complications of lupus with an incidence of 3-9%. It usually presents with non-specific symptoms such as dyspnea, orthopnea, chest pain, pedal edema, fever, diaphoresis, paroxysmal nocturnal dyspnea, nausea, vomiting, or palpitations. Even though endomyocardial biopsy is considered the gold standard diagnostic approach, other non-invasive diagnostic alternatives including cardiac magnetic resonance (CMR) have been studied. Therapeutic interventions may range from high-dose steroids, and IVIG, to the most advanced strategies such as mechanical circulatory support including VenoArterial Extracorporeal Membrane Oxygenation (VA-ECMO), and Impella, among others.