Room temperature MgI2-catalyzed Friedel–Crafts reaction between electron-rich (het)arenes and ethyl glyoxylate

Room temperature MgI2-catalyzed Friedel–Crafts reaction between electron-rich (het)arenes and ethyl glyoxylate

[Display omitted] Magnesium iodide-catalyzed addition of electron-rich (het)arenes to ethyl glyoxylate proceeds at room temperature with high chemoselectivity to afford ethyl 2-(het)aryl- 2-hydroxyacetates in yields up to 95%.

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Bibliographic Details
Published in:Mendeleev communications Vol. 28; no. 4; pp. 429 - 430
Main Authors: Feofanov, Mikhail N., Lozhkin, Boris A., Anokhin, Maksim V., Averin, Alexey D., Beletskaya, Irina P.
Format: Journal Article
Language:English
Published: Elsevier B.V 01-07-2018
Online Access:Get full text
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Description
Summary:[Display omitted] Magnesium iodide-catalyzed addition of electron-rich (het)arenes to ethyl glyoxylate proceeds at room temperature with high chemoselectivity to afford ethyl 2-(het)aryl- 2-hydroxyacetates in yields up to 95%.
ISSN:0959-9436
DOI:10.1016/j.mencom.2018.07.030