Disorders of spatial working memory in affective disorders with mild current depression and their neurophysiological correlates

• Published in: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova Vol. 119; no. 10; p. 56
• Main Authors: Galkin, S A, Peshkovskaya, A G, Simutkin, G G, Vasil'eva, S N, Roshchina, O V, Ivanova, S A, Bokhan, N A
• Format: Journal Article
• Language: Russian
• Published: Russia (Federation) 2019
• Subjects: Adult; Depression; Depressive Disorder - complications; Depressive Disorder - physiopathology; Electroencephalography; Humans; Memory Disorders - complications; Memory, Short-Term; Middle Aged; Mood Disorders; Theta Rhythm; depression; cognitive functions; electroencephalographic correlates; spatial working memory
• ISSN: 1997-7298
• DOI: 10.17116/jnevro201911910156

To assess spatial working memory disorders in patients with mild depressive disorders and determine their neurophysiological correlates.
Thirty patients (right-handed) with ICD-10 diagnosis Mood Disorders (F31.3, F32.0, F33.0, F34.1), aged 37±8 years, were examined before treatment. A control group included 30 mentally and somatically healthy individuals (32±7 years old). The study of spatial working memory was carried out using the Corsi Block-Tapping test. EEG was recorded and the values of the spectral power of theta, alpha and beta rhythms were analyzed.
A decrease in the level of working memory that was correlated with higher values of theta rhythm power in the frontal and occipital regions and alpha rhythm in the frontal cortex was observed in affective disorders with mild depressive symptoms.