Catecholase, phenoxazinone synthase and copper (CuII) complex based on pyrazolic ligand: Preparation and characterization

• Published in: Materials today : proceedings Vol. 72; pp. 3514 - 3520
• Main Authors: El Boutaybi, Mohamed, Bouroumane, Nadia, Azzouzi, Mohamed, Bacroume, Said, Touzani, Rachid, Bahari, Zahra
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 2023
• Subjects: Catalytic properties; Catechol; Copper (II); O-quinone; Oxidation; Catalytic properties; Catechol; Oxidation; O-quinone; Copper (II)
• ISSN: 2214-7853; 2214-7853
• DOI: 10.1016/j.matpr.2022.08.234

The high catalytic activity of catechol oxidation in atmospheric oxygen signified the selectivity and efficiency of the metalloenzyme [CuSO4L], with L is 5 chloro-N-((3,5-dimethyl-1H-pyrazol-1-yl)methyl)pyridin-2-amine. In this study, two parameters influencing the catecholase activity were examined: the nature of solvent and the nature of the complex. The best activity of catechol oxidation is given by the synthesized complex in methanol solvent with the rate of 1.7 μmol/L min−1. In the contrary, the prepared complex in situ (weak catalyst) showed weak value in the oxidation rate (0.14 μmol/L min−1) in DMSO.
However, our complex synthesized in good yield was subjected to several spectral and thermal analyses to verify the results obtained.