Alcaloides das cascas das raízes de Zanthoxylum spp

• Published in: Química Nova Vol. 35; no. 11; pp. 2173 - 2176
• Main Authors: Hohlemwerger, Sandra Virgínia Alves, Sales, Edijane Matos, Costa, Rafael dos Santos, Velozo, Eudes da Silva, Guedes, Maria Lenise da Silva
• Format: Journal Article
• Language: English
• Published: Sociedade Brasileira de Química 2012
• Subjects: Z. rhoifolium; Z. stelligerum; Zanthoxylum tingoassuiba
• ISSN: 0100-4042; 1678-7064
• DOI: 10.1590/S0100-40422012001100013

In 1959, Gottlieb and Antonaccio published a study reporting the occurrence of lignan sesamin and triterpene lupeol in Zanthoxylum tingoassuiba. In this work we describe the phytochemical study of the root bark of the Z. tingoassuiba which allowed the identification of the lupeol, sesamin, and alkaloids dihydrochelerythrine, chelerythrine, anorttianamide, cis-N-methyl-canadine, predicentine, 2, 3-methylenedioxy-10,11-dimethoxy-tetrahydro protoberberine. The investigation of hexane and methanol extracts of the root bark of Z. rhoifolium and Z. stelligerum also investigated showed the presence of alkaloids dihydrochelerythrine, anorttianamide, cis-N-methyl-canadine, 7,9-dimethoxy-2,3-methylenedioxybenzophenanthridine and angoline. The occurrence of 2,3-methylenedioxy-10,11-dimethoxy-tetrahydro protoberberine is first described in Z. tingoassuiba and Z. stelligerum. This is also the first report of the presence of hesperidin and neohesperidin in roots of Z. stelligerum.