Efficiency of surgical treatment of multidrug-resistant Pulmonary Tuberculosis within the DOTS-PLUS program

• Published in: Bi͡u︡lletenʹ Sibirskoĭ medit͡s︡iny Vol. 8; no. 1; pp. 85 - 91
• Main Authors: A. K. Strelis, A. A. Strelis, O. V. Anastasov, Ye. V. Nekrasov, V. K. Raskoshnykh, A. I. Zadorozniy, Ye. A. Gubin, D. Yu. Schegertzov, O. Yu. Khristenko, G. V. Yanova
• Format: Journal Article
• Language: English
• Published: Siberian State Medical University (Tomsk) 28-02-2009
• Subjects: множественная лекарственная устойчивость; туберкулез легких; хирургическое лечение
• ISSN: 1682-0363; 1819-3684
• DOI: 10.20538/1682-0363-2009-1-85-91

Efficiency of the surgical treatment of pulmonary tuberculosis for multidrug-resistant (MDR TB) tuberculosis patients was analyzed. Seventy DOTS-PLUS patients with various clinical forms of pulmonary tuberculosis and Mycobacterium resistance from 3 to 8 antituberculosis drugs have been operated. Positive clinical results have been achieved for 65 (92,8%) patients. Indications for surgical treatment for patients with MDR TB have been developed. To ensure positive outcomes of the surgical interventions, main objective is the development of so-called a favorable preoperative environment during the preoperative phase. It includes switching on intensive chemotherapy and pathogenetic methods of treatment.