Lumbar Degenerative Spondylolisthesis Is Not Always Unstable: Clinicobiomechanical Evidence

• Published in: Spine (Philadelphia, Pa. 1976) Vol. 39; no. 26; pp. 2127 - 2135
• Main Authors: Hasegawa, Kazuhiro, Kitahara, Ko, Shimoda, Haruka, Ishii, Keiji, Ono, Masatoshi, Homma, Takao, Watanabe, Kei
• Format: Journal Article
• Language: English
• Published: United States by Lippincott Williams & Wilkins 15-12-2014
• Subjects: Aged; Biomechanical Phenomena - physiology; Female; Humans; Joint Instability - physiopathology; Joint Instability - surgery; Low Back Pain - physiopathology; Low Back Pain - surgery; Lumbar Vertebrae - physiopathology; Lumbar Vertebrae - surgery; Male; Middle Aged; Spinal Stenosis - physiopathology; Spinal Stenosis - surgery; Spondylolisthesis - physiopathology; Spondylolisthesis - surgery; Treatment Outcome
• ISSN: 0362-2436; 1528-1159
• DOI: 10.1097/BRS.0000000000000621

STUDY DESIGN.A clinicobiomechanical study.
OBJECTIVE.To clarify the clinicobiomechanical characteristics of a segment with lumbar degenerative spondylolisthesis (LDS) using an original intraoperative measurement system.
SUMMARY OF BACKGROUND DATA.Although radiographical evaluation of LDS is extensively performed, the diagnosis of segmental instability remains controversial. The intraoperative measurement system used in this study is the first clinically available system that performs cyclic flexion-extension displacement of the segment with all ligamentous structures intact and can determine both the stiffness (N/mm) and neutral zone (NZ, [mm/N]).
METHODS.Forty-eight patients with LDS (males/females = 19/29, 68.5 yr; group D) were compared with 48 patients with lumbar spinal stenosis without LDS (males/females = 33/15, 64.8 yr, group N) in terms of symptoms, radiological, and biomechanical results. Instability was defined as a segment with NZ more than 2 mm. Symptoms (36-Item Short Form Health Survey), radiographical findings (radiographs, magnetic resonance images, computed tomographic scans), stiffness, NZ, and frequency of instability were also compared. Risk factors for instability were analyzed by multivariate logistic regression with a forward stepwise procedure.
RESULTS.None of the physical function categories or radiological findings of 36-Item Short Form Health Survey and low back pain (visual analogue scale) differed significantly between the groups. Although NZ was significantly greater in group D (1.97) than in group N (1.73) (P < 0.05), the frequency of instability did not differ significantly between groups. Facet opening (odds ratio, 11.0; P < 0.01) and facet type (odds ratio, 6.0; P < 0.05) were significant risk factors for instability.
CONCLUSION.Neither the symptoms nor the frequency of instability differed significantly between groups. The radiological findings of spondylolisthesis did not indicate instability, but facet opening and sagittally oriented facets were indicative of instability. The results of this study demonstrated that LDS is not always unstable in the measurement setting, suggesting that the instability of LDS can stabilize spontaneously during the natural course.Level of EvidenceN/A