Evaluation of protein Z plasma level in beta-thalassemia major patients in Ahvaz city in Iran

OBJECTIVES： Thrombotic episodes occurred frequently in beta-thalassemia major （BTM） patients, leading tohypercoagulability of plasma. Protein Z （PZ） is a vitamin-K-dependent anti-coagulation factor that plays a role in thehuman homeostatic process. The objective of the current study is to investigat...

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Bibliographic Details
Published in:	Frontiers in biology Vol. 12; no. 6; pp. 442 - 447
Main Authors:	Jalali, Mohammad Taha, Absalan, Abdorrahim, Mohseni, Alireza, Kaydani, Gholam Abbas, Zayeri, Zeinab Deris
Format:	Journal Article
Language:	English
Published:	Beijing Higher Education Press 01-12-2017 Springer Nature B.V
Subjects:	Biochemistry Biomedical and Life Sciences Blood Cell Biology Developmental Biology Epidemiology Erythrocytes Genetics and Population Dynamics Life Sciences major;beta-thalassemia,;protein;Z,;thrombosis,;immunoassay,;anti-coagulation;factor Neurobiology Plasma Plasma levels Proteomics Research Article Statistical analysis Thalassemia Thromboembolism Iran protein Z anti-coagulation factor thrombosis major beta-thalassemia immunoassay
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Summary:	OBJECTIVES： Thrombotic episodes occurred frequently in beta-thalassemia major （BTM） patients, leading tohypercoagulability of plasma. Protein Z （PZ） is a vitamin-K-dependent anti-coagulation factor that plays a role in thehuman homeostatic process. The objective of the current study is to investigate the distribution pattern of PZ plasmaconcentrations between BTM patients and the normal population in Ahvaz city, the center of Khuzestan province, southwest ofIran.
Bibliography:	11-5892/Q
ISSN:	1674-7984 1674-7992
DOI:	10.1007/s11515-017-1469-8