Taxol (paclitaxel): strategies to increase the supply of a new anticancer drug

Taxol (paclitaxel): strategies to increase the supply of a new anticancer drug

Taxol (paclitaxel) has been hailed by many as the most promising new cancer treatment in two decades. The FDA requires that paclitaxel intended for human consumption be obtained only from the bark of Taxus brevifolia, the Pacific yew. As this may become increasingly uneconomical, new strategies must...

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Bibliographic Details
Published in:Applied biochemistry and biotechnology Vol. 54; no. 1/3; pp. 133 - 140
Main Authors: Stull, D.P. (Hauser Chemical Research, Inc., Boulder, CO.), Scales, T.A, Daughenbaugh, R, Jans, N.A, Bailey, D.T
Format: Journal Article
Language:English
Published: 01-07-1995
Subjects:
COMPOSICION QUIMICA
COMPOSITION CHIMIQUE
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Summary:Taxol (paclitaxel) has been hailed by many as the most promising new cancer treatment in two decades. The FDA requires that paclitaxel intended for human consumption be obtained only from the bark of Taxus brevifolia, the Pacific yew. As this may become increasingly uneconomical, new strategies must be explored to ensure the continued availability of taxol and related molecules. This article examines the planning that must be engaged in and the contingencies that must be prepared for in this changing arena
Bibliography:F60
9706435
Q60
ISSN:0273-2289
1559-0291
DOI:10.1007/BF02787915