Amyloid-β hypothesis in Alzheimer's disease and neurotoxicity of oligomeric amyloid through glial cells

Abstract Amyloid hypothesis is considered to be the most feasible hypothesis for the pathogenesis of Alzheimer's disease ( AD ). Based on this hypothesis, various therapeutic approaches were examined for AD . In this issue, Horiuchi et al. showed oligomeric amyloid‐β causes glia‐mediated excito...

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Bibliographic Details
Published in:Clinical & experimental neuroimmunology Vol. 6; no. 2; pp. 116 - 117
Main Author: Asakura, Kunihiko
Format: Journal Article
Language:English
Published: Blackwell Publishing Ltd 01-05-2015
Online Access:Get full text
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Summary:Abstract Amyloid hypothesis is considered to be the most feasible hypothesis for the pathogenesis of Alzheimer's disease ( AD ). Based on this hypothesis, various therapeutic approaches were examined for AD . In this issue, Horiuchi et al. showed oligomeric amyloid‐β causes glia‐mediated excitotoxicity in vitro , which might introduce another approach for the treatment of AD .
Bibliography:ark:/67375/WNG-H1XGQ2J1-7
ArticleID:CEN312205
istex:5A12437EA73630ADCAA7FD82BBF6D260AAAFA9D3
ISSN:1759-1961
1759-1961
DOI:10.1111/cen3.12205