cDNA cloning and sequence analysis of pluripotency genes in tree shrews (Tupaia belangeri)

In this paper, partial sequences of the tree shrew (Tupaia belangeri) Klf4, Sox2, and c-Myc genes were cloned and sequenced, which were 382, 612, and 485 bp in length and encoded 127, 204, and 161 amino acids, respectively. Whereas, their cDNA sequence identities with those of human were 89%, 98%, a...

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Bibliographic Details
Published in:	Dōngwùxué yánjiū Vol. 34; no. 2; p. 127
Main Authors:	Wang, Cai-Yun, Ma, Yun-Han, He, Da-Jian, Yang, Shi-Hua
Format:	Journal Article
Language:	Chinese English
Published:	China 01-04-2013
Subjects:	Amino Acid Sequence Animals Base Sequence Cattle Cloning, Molecular DNA, Complementary - genetics Female Humans Male Mammals - classification Mammals - genetics Mice Molecular Sequence Data Open Reading Frames Phylogeny Proteins - genetics Rats Sequence Alignment Tupaia - genetics Sox2 Tree shrew Klf4 c-Myc Sequence analysis
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Summary:	In this paper, partial sequences of the tree shrew (Tupaia belangeri) Klf4, Sox2, and c-Myc genes were cloned and sequenced, which were 382, 612, and 485 bp in length and encoded 127, 204, and 161 amino acids, respectively. Whereas, their cDNA sequence identities with those of human were 89%, 98%, and 89%, respectively. Their phylogenetic tree results indicated different topologies and suggested individual evolutional pathways. These results can facilitate further functional studies.
ISSN:	0254-5853
DOI:	10.3724/SP.J.1141.2013.02127